Tissue-Specific Activities of SARM-ASK1-MKK3 Signaling Coordinate Immunity and Behavior to Pathogenic and Nutritional Bacteria in C. elegans

Microbes represent both an essential source of nutrition and a potential source of lethal infection to the nematode Caenorhabditis elegans. Immunity in C. elegans requires a signaling module comprised of orthologs of the mammalian Toll-interleukin-1 receptor (TIR) domain protein SARM, the mitogen-ac...

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Bibliographic Details
Main Authors: Kim, Dennis H., Pagano, Daniel Joseph, Kooistra, Tristan G., Chu, Stephanie W., Shivers, Robert P.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cell Press 2010
Subjects:
Online Access:http://hdl.handle.net/1721.1/56561
https://orcid.org/0000-0002-4109-5152