Dynamic association of the replication initiator and transcription factor DnaA with the Bacillus subtilis chromosome during replication stress

DnaA functions as both a transcription factor and the replication initiator in bacteria. We characterized the DNA binding dynamics of DnaA on a genomic level. Based on cross-linking and chromatin immunoprecipitation data, DnaA binds at least 17 loci, 15 of which are regulated transcriptionally in re...

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Bibliographic Details
Main Authors: Breier, Adam M., Grossman, Alan Davis
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Society for Microbiology 2010
Subjects:
Online Access:http://hdl.handle.net/1721.1/57484
https://orcid.org/0000-0002-8235-7227