A model for genetic and epigenetic regulatory networks identifies rare for transcription factor induced pluripotency
With relatively low efficiency, differentiated cells can be reprogrammed to a pluripotent state by ectopic expression of a few transcription factors. An understanding of the mechanisms that underlie data emerging from such experiments can help design optimal strategies for creating pluripotent cells...
Main Authors: | Artyomov, Maxim N., Meissner, Alexander, Chakraborty, Arup K. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2010
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Online Access: | http://hdl.handle.net/1721.1/57580 https://orcid.org/0000-0003-1268-9602 |
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