Systematic calibration of a cell signaling network model

Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental data is often challenging and a rate limiting step in model development. To address this problem, we developed a systemat...

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Bibliographic Details
Main Authors: Kim, Kyoung A.E., Spencer, Sabrina L., Albeck, John G., Burke, John M., Sorger, Peter K., Gaudet, Suzanne, Kim, Do Hyun
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58679