Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence

Background: The malaria parasite Plasmodium falciparum exhibits abundant genetic diversity, and this diversity is key to its success as a pathogen. Previous efforts to study genetic diversity in P. falciparum have begun to elucidate the demographic history of the species, as well as patterns of popu...

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Bibliographic Details
Main Authors: Neafsey, Daniel E., Volkman, Sarak K., Park, Daniel, Montgomery, Philip, Milner, Danny A., Lukens, Amanda K., Rosen, David, Daniels, Rachel F., Houde, Nathan, Cortese, Joseph F., Tyndall, Erin, Gates, Casey, Stange-Thomann, Nicole, Sarr, Ousmane, Ndiaye, Daouda, Ndir, Omar, Mboup, Soulyemane, Ferreira, Marcelo U., do Lago Moraes, Sandra, Dash, Aditya P., Chitnis, Chetan E., Wiegand, Roger C., Hartl, Daniel L., Birren, Bruce W., Wirth, Dyann F., Schaffner, Stephen F, Lander, Eric Steven, Sabeti, Pardis
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58718