Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic trees and protein structure prediction. Numerous studies have shown that the incorporation of predicted secondary structure...
Main Authors: | Ohlson, Tomas, Aggarwal, Varun, Elofsson, Arne, MacCallum, Robert M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2010
|
Online Access: | http://hdl.handle.net/1721.1/58739 |
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