Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins

Background: Kinetochores are large multi-protein structures that assemble on centromeric DNA (CEN DNA) and mediate the binding of chromosomes to microtubules. Comprising 125 base-pairs of CEN DNA and 70 or more protein components, Saccharomyces cerevisiae kinetochores are among the best understood....

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Bibliographic Details
Main Authors: Meraldi, Patrick, McAinsh, Andrew D., Rheinbay, Esther, Sorger, Peter K.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58854