Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins
Background: Kinetochores are large multi-protein structures that assemble on centromeric DNA (CEN DNA) and mediate the binding of chromosomes to microtubules. Comprising 125 base-pairs of CEN DNA and 70 or more protein components, Saccharomyces cerevisiae kinetochores are among the best understood....
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Format: | Article |
Language: | English |
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BioMed Central Ltd
2010
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Online Access: | http://hdl.handle.net/1721.1/58854 |