Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins

Background: The regeneration of peripheral nerve is associated with a change in the alternative splicing of the fibronectin primary gene transcript to re-express embryonic isoforms containing a binding site for α4β1 integrins that promote neurite outgrowth. Here we use PC12 cells to examine the role...

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Dettagli Bibliografici
Autori principali: Vogelezang, Mariette, Forster, Ulrike B, Han, Jaewon, Ginsberg, Mark H, ffrench-Constant, Charles
Altri autori: Koch Institute for Integrative Cancer Research at MIT
Natura: Articolo
Lingua:English
Pubblicazione: BioMed Central Ltd 2010
Accesso online:http://hdl.handle.net/1721.1/58897