Positive selection for unpreferred codon usage in eukaryotic genomes

Background: Natural selection has traditionally been understood as a force responsible for pushing genes to states of higher translational efficiency, whereas lower translational efficiency has been explained by neutral mutation and genetic drift. We looked for evidence of directional selection resu...

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Bibliographic Details
Main Authors: Neafsey, Daniel E., Galagan, James E.
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/58902