Lipid-Coated Biodegradable Particles as "Synthetic Pathogens" for Vaccine Engineering

The physicochemical context in which molecules are presented at the surfaces of microbes has tremendous implications for the immune response to vaccination. The spacing and mobility of molecules may control interactions of their receptors, influencing immune cell activation, pathogen uptake, and ant...

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Bibliographic Details
Main Authors: Chaparro, Jose P., Bershteyn, Anna, Riley, E. B., Yao, R. S., Zachariah, Roshini Sarah, Irvine, Darrell J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Institute of Electrical and Electronics Engineers 2010
Online Access:http://hdl.handle.net/1721.1/58904