Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae

Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae

Background: The FHIT gene is lost early in the development of many tumors. Fhit possesses intrinsic ApppA hydrolase activity though ApppA cleavage is not required for tumor suppression. Because a mutant form of Fhit that is functional in tumor suppression and defective in catalysis binds ApppA well,...

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Bibliographic Details
Main Authors: Rubio-Texeira, Marta, Varnum, James M, Bieganowski, Pawel, Brenner, Charles
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/59012

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http://hdl.handle.net/1721.1/59012

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