Using Topology of the Metabolic Network to Predict Viability of Mutant Strains

Background: Understanding the relationships between the structure (topology) and function of biological networks is a central question of systems biology. The idea that topology is a major determinant of systems function has become an attractive and highly-disputed hypothesis. While the structural a...

Full description

Bibliographic Details
Main Authors: Mirny, Leonid A., Wunderlich, Zeba
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/59195
https://orcid.org/0000-0002-0785-5410