High-throughput gene expression profiling of memory differentiation in primary human T cells

Background: The differentiation of naive T and B cells into memory lymphocytes is essential for immunity to pathogens. Therapeutic manipulation of this cellular differentiation program could improve vaccine efficacy and the in vitro expansion of memory cells. However, chemical screens to identify co...

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Bibliographic Details
Main Authors: Angelosanto, Jill, Brosnahan, Kathleen, Ross, Kenneth, Hahn, Cynthia, Russell, Kate, Drury, Linda, Norton, Stephanie, Nadler, Lee, Stegmaier, Kimberly, Haining, W. Nicholas
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:English
Published: BioMed Central Ltd 2010
Online Access:http://hdl.handle.net/1721.1/59279