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Position specific variation in the rate of evolution in transcription factor binding sites

Position specific variation in the rate of evolution in transcription factor binding sites

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Background: The binding sites of sequence specific transcription factors are an important and relatively well-understood class of functional non-coding DNAs. Although a wide variety of experimental and computational methods have been developed to characterize transcription factor binding sites, they...

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Bibliographic Details
Main Authors: Kellis, Manolis, Moses, Alan M., Chiang, Derek Y., Eisen, Michael B., Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Software
Language:English
Published: BioMed Central Ltd 2010
Subjects:
Artifacts
Base composition
Base sequence
Binding sites, genetics
Computational biology, methods
Computational biology, statistics & numerical data
Conserved sequence
Evolution, molecular
Gene expression regulation, fungal
Genetic variation
Genome, fungal
Mutagenesis
Predictive value of tests
Promoter regions, genetic
Promoter regions, genetic, physiology
Saccharomyces, genetics
Saccharomyces cerevisiae, genetics
Transcription factors, genetics
Transcription factors, metabolism
Transcription, genetic
Online Access:http://hdl.handle.net/1721.1/59308
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http://hdl.handle.net/1721.1/59308

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