Unbiased, Genome-Wide In Vivo Mapping of Transcriptional Regulatory Elements Reveals Sex Differences in Chromatin Structure Associated with Sex-Specific Liver Gene Expression

We have used a simple and efficient method to identify condition-specific transcriptional regulatory sites in vivo to help elucidate the molecular basis of sex-related differences in transcription, which are widespread in mammalian tissues and affect normal physiology, drug response, inflammation, a...

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Bibliographic Details
Main Authors: Ling, Guoyu, Sugathan, Aarathi, Mazor, Tali, Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Society for Microbiology 2010
Online Access:http://hdl.handle.net/1721.1/60028
https://orcid.org/0000-0001-9249-8181