miTuner - a kit for microRNA based gene expression tuning in mammalian cells

The purpose of this RFC is to introduce a modular expression tuning kit for use in mammalian cells. The kit enables the regulation of the gene expression of any gene of interest (GOI) based on synthetic microRNAs, endogenous microRNAs or a combination of both.

Bibliographic Details
Main Authors: Adlung, Lorenz, Sabah, Jude Al, Bayer, Philipp, Berrens, Rebecca, Cristiano, Elena, Flocke, Lea, Kleinsorg, Stefan, Kolodziejczyk, Aleksandra, Kraemer, Stephen, Torre, Alejandro Macias, Mathur, Aastha, Mayilo, Dmytro, Neumann, Stefan, Niopek, Dominik, Pisa, Rudolf, Schad, Jan-Ulrich, Schumacher, Laura-Nadine, Uhlig, Thomas, Wu, Xiaoting, Keienburg, Jens, Boerner, Kathleen, Grimm, Dirk, Eils, Roland
Format: Technical Report
Language:English
Published: 2010
Online Access:http://hdl.handle.net/1721.1/60091