Ketogenic essential amino acids modulate lipid synthetic pathways and hepatic steatosis in mice

Background Although dietary ketogenic essential amino acid (KAA) content modifies accumulation of hepatic lipids, the molecular interactions between KAAs and lipid metabolism are yet to be fully elucidated. Methodology/Principal Findings We designed a diet with a high ratio (E/N) of essential...

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Bibliographic Details
Main Authors: Noguchi, Yasushi, Nishikata, Natsumi, Shikata, Nahoko, Kimura, Yoshiko, Aleman, Jose O., Young, Jamey D., Koyama, Naoto, Kelleher, Joanne Keene, Takahashi, Michio, Stephanopoulos, Gregory
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2010
Online Access:http://hdl.handle.net/1721.1/60308
https://orcid.org/0000-0002-8676-5738
https://orcid.org/0000-0001-6909-4568