Innate Immune Suppression Enables Frequent Transfection with RNA Encoding Reprogramming Proteins

Background Generating autologous pluripotent stem cells for therapeutic applications will require the development of efficient DNA-free reprogramming techniques. Transfecting cells with in vitro-transcribed, protein-encoding RNA is a straightforward method of directly expressing high levels of re...

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Detalhes bibliográficos
Main Authors: Angel, Matthew, Yanik, Mehmet Fatih
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:en_US
Publicado em: Public Library of Science 2010
Acesso em linha:http://hdl.handle.net/1721.1/60359