The AAA+ ClpX machine unfolds a keystone subunit to remodel the Mu transpososome

A hyperstable complex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA replication. ClpX, a AAA+ enzyme, fulfills this function by unfolding one transpososome subunit. Which MuA subunit is extracted, and how complex destabilization relates to establishm...

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Bibliographic Details
Main Authors: Baker, Tania, Abdelhakim, Aliaa H., Sauer, Robert T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/61360
https://orcid.org/0000-0002-1719-5399