A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase

The only Y-family DNA polymerase conserved among all domains of life, DinB and its mammalian ortholog pol κ, catalyzes proficient bypass of damaged DNA in translesion synthesis (TLS). Y-family DNA polymerases, including DinB, have been implicated in diverse biological phenomena ranging from adaptive...

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Bibliographic Details
Main Authors: Walker, Graham C., Jarosz, Daniel F., Delaney, James C., Essigmann, John M., Cohen, Susan E., Ph. D. Massachusetts Institute of Technology
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/61367
https://orcid.org/0000-0001-6159-0778
https://orcid.org/0000-0001-7243-8261
https://orcid.org/0000-0002-2196-5691