A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase
The only Y-family DNA polymerase conserved among all domains of life, DinB and its mammalian ortholog pol κ, catalyzes proficient bypass of damaged DNA in translesion synthesis (TLS). Y-family DNA polymerases, including DinB, have been implicated in diverse biological phenomena ranging from adaptive...
Main Authors: | Walker, Graham C., Jarosz, Daniel F., Delaney, James C., Essigmann, John M., Cohen, Susan E., Ph. D. Massachusetts Institute of Technology |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2011
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Online Access: | http://hdl.handle.net/1721.1/61367 https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0001-7243-8261 https://orcid.org/0000-0002-2196-5691 |
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