mTORC1 Activates SREBP-1c and Uncouples Lipogenesis From Gluconeogenesis
Insulin resistance, which is defined as the inability of insulin to promote efficient glucose uptake by peripheral tissues, is a metabolic condition associated with obesity, type 2 diabetes, dyslipidemia, and cardiovascular diseases. Although important advances in our understanding of the molecular...
Main Authors: | , |
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Format: | Article |
Language: | en_US |
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National Academy of Sciences
2011
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Online Access: | http://hdl.handle.net/1721.1/61405 https://orcid.org/0000-0002-1446-7256 |