Transcript counting in single cells reveals dynamics of rDNA transcription
Most eukaryotes contain many tandem repeats of ribosomal RNA genes of which only a subset is transcribed at any given time. Current biochemical methods allow for the determination of the fraction of transcribing repeats (ON) versus non-transcribing repeats (OFF) but do not provide any dynamical info...
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| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2011
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| Online Access: | http://hdl.handle.net/1721.1/61692 |