Controlled Delivery of Transforming Growth Factor β1 by Self-Assembling Peptide Hydrogels Induces Chondrogenesis of Bone Marrow Stromal Cells and Modulates Smad2/3 Signaling

Self-assembling peptide hydrogels were modified to deliver transforming growth factor b1 [beta 1](TGF-b1)[TGF beta 1] to encapsulated bone-marrow-derived stromal cells (BMSCs) for cartilage tissue engineering applications using two different approaches: (i) biotin-streptavidin tethering; (ii) adso...

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Bibliographic Details
Main Authors: Kopesky, Paul Wayne, Vanderploeg, Eric J., Kisiday, John D., Frisbie, David D., Grodzinsky, Alan J.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:en_US
Published: Mary Ann Liebert 2011
Online Access:http://hdl.handle.net/1721.1/62026
https://orcid.org/0000-0003-0026-6215
https://orcid.org/0000-0002-4942-3456