Discrete logic modelling as a means to link protein signalling networks functional analysis of mammalian signal transduction

Discrete logic modelling as a means to link protein signalling networks functional analysis of mammalian signal transduction

Large-scale protein signalling networks are useful for exploring complex biochemical pathways but do not reveal how pathways respond to specific stimuli. Such specificity is critical for understanding disease and designing drugs. Here we describe a computational approach—implemented in the free CNO...

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Bibliographic Details
Main Authors: Saez-Rodriguez, Julio, Alexopoulos, Leonidas G., Epperlein, Jonathan, Samaga, Regina, Lauffenburger, Douglas A., Klamt, Steffen, Sorger, Peter K.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: EMBO and Macmillan Publishers Limited 2011
Online Access:http://hdl.handle.net/1721.1/62180

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http://hdl.handle.net/1721.1/62180

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