Mutations in Bone Marrow-Derived Stromal Stem Cells Unmask Latent Malignancy

Mutations in Bone Marrow-Derived Stromal Stem Cells Unmask Latent Malignancy

Neoplastic epithelia may remain dormant and clinically unapparent in human patients for decades. Multiple risk factors including mutations in tumor cells or the stromal cells may affect the switch from dormancy to malignancy. Gene mutations, including p53 mutations, within the stroma of tumors are a...

Full description

Bibliographic Details
Main Authors: Houghton, JeanMarie, Li, Hanchen, Fan, Xueli, Liu, Yingwang, Liu, Jian Hua, Rao, Varada P., Poutahidis, Theofilos, Taylor, Christie L., Jackson, Erin A., Hewes, Christine M., Lyle, Stephen, Cerny, Anna, Bowen, Glennice, Cerny, Jan, Moore, Nathan, Kurt-Jones, Evelyn A., Erdman, Susan E.
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine
Format: Article
Language:en_US
Published: Mary Ann Liebert 2011
Online Access:http://hdl.handle.net/1721.1/62305

Internet

http://hdl.handle.net/1721.1/62305

Similar Items