Nanometric self-assembling peptide layers maintain adult hepatocyte phenotype in sandwich cultures

Nanometric self-assembling peptide layers maintain adult hepatocyte phenotype in sandwich cultures

Background: Isolated hepatocytes removed from their microenvironment soon lose their hepatospecific functions when cultured. Normally hepatocytes are commonly maintained under limited culture medium supply as well as scaffold thickness. Thus, the cells are forced into metabolic stress that degenerat...

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Bibliographic Details
Main Authors: Wu, Jonathan, Mari-Buye, Nuria, Fernandez Muinos, Teresa, Borros, Salvador, Favia, Pietro, Semino, Carlos Eduardo
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:English
Published: BioMed Central Ltd 2011
Online Access:http://hdl.handle.net/1721.1/62813

Internet

http://hdl.handle.net/1721.1/62813

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