A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development

RNA interference (RNAi) is a powerful strategy for studying the phenotypic consequences of reduced gene expression levels in model systems. To develop a method for the rapid characterization of the developmental consequences of gene dysregulation, we tested the use of RNAi for “transient transgenic”...

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Bibliografiske detaljer
Main Authors: Bjork, Bryan C., Fujiwara, Yuko, Davis, Shannon W., Qiu, Haiyan, Saunders, Thomas L., Sandy, Peter, Orkin, Stuart H., Camper, Sally A., Beier, David R.
Andre forfattere: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Sprog:en_US
Udgivet: Public Library of Science 2011
Online adgang:http://hdl.handle.net/1721.1/63160