Co-Evolution of Transcriptional Silencing Proteins and the DNA Elements Specifying Their Assembly

Co-evolution of transcriptional regulatory proteins and their sites of action has been often hypothesized but rarely demonstrated. Here we provide experimental evidence of such co-evolution in yeast silent chromatin, a finding that emerged from studies of hybrids formed between two closely related S...

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Bibliographic Details
Main Authors: Zill, Oliver A., Scannell, Devin, Teytelman, Leonid, Rine, Jasper
Other Authors: Massachusetts Institute of Technology. Materials Processing Center
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/63599