A homolog of tocopherol C-methyltransferases catalyzes N-methylation in anticancer alkaloid biosynthesis

Madagascar periwinkle (Catharanthus roseus) is the sole source of the anticancer drugs vinblastine and vincristine, bisindole alkaloids derived from the dimerization of the terpenoid indole alkaloids vindoline and catharanthine. Full elucidation of the biosynthetic pathways of these compounds is a p...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Liscombe, David K., Usera, Aimee R., O'Connor, Sarah Ellen
अन्य लेखक: Massachusetts Institute of Technology. Department of Chemistry
स्वरूप: लेख
भाषा:en_US
प्रकाशित: National Academy of Sciences (U.S.) 2011
ऑनलाइन पहुंच:http://hdl.handle.net/1721.1/64435