Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex

Brain stimulation and imaging studies in humans have highlighted a key role for the prefrontal cortex in clinical depression; however, it remains unknown whether excitation or inhibition of prefrontal cortical neuronal activity is associated with antidepressant responses. Here, we examined cellular...

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Bibliographic Details
Main Authors: Covington III, Herbert E., Lobo, Mary Kay, Maze, Ian, Vialou, Vincent, Hyman, James M., Zaman, Samir, LaPlant, Quincey C., Mouzon, Ezekiel, Ghose, Subroto, Tamminga, Carol A., Neve, Rachael L., Deisseroth, Karl, Nestler, Eric J.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2011
Online Access:http://hdl.handle.net/1721.1/64463
https://orcid.org/0000-0002-3854-5968