Structural basis for the inhibition of human alkyladenine DNA by 3,N4-ethenocytosine containing DNA

Reactive oxygen and nitrogen species, generated by neutrophils and macrophages in chronically inflamed tissues, readily damage DNA, producing a variety of potentially genotoxic etheno base lesions; such inflammation-related DNA damage is now known to contribute to carcinogenesis. Although the human...

Full description

Bibliographic Details
Main Authors: Lingaraju, Gondichatnahalli M., Davis, Christopher A., Setser, Jeremy Wayne, Samson, Leona D, Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: American Society for Biochemistry and Molecular Biology, Inc. 2011
Online Access:http://hdl.handle.net/1721.1/64727
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0002-7112-1454