Structural basis for the inhibition of human alkyladenine DNA by 3,N4-ethenocytosine containing DNA
Reactive oxygen and nitrogen species, generated by neutrophils and macrophages in chronically inflamed tissues, readily damage DNA, producing a variety of potentially genotoxic etheno base lesions; such inflammation-related DNA damage is now known to contribute to carcinogenesis. Although the human...
Main Authors: | , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Society for Biochemistry and Molecular Biology, Inc.
2011
|
Online Access: | http://hdl.handle.net/1721.1/64727 https://orcid.org/0000-0001-5486-2755 https://orcid.org/0000-0002-7112-1454 |