Structural basis for the inhibition of human alkyladenine DNA by 3,N4-ethenocytosine containing DNA
Reactive oxygen and nitrogen species, generated by neutrophils and macrophages in chronically inflamed tissues, readily damage DNA, producing a variety of potentially genotoxic etheno base lesions; such inflammation-related DNA damage is now known to contribute to carcinogenesis. Although the human...
Main Authors: | Lingaraju, Gondichatnahalli M., Davis, Christopher A., Setser, Jeremy Wayne, Samson, Leona D, Drennan, Catherine L |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Language: | en_US |
Published: |
American Society for Biochemistry and Molecular Biology, Inc.
2011
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Online Access: | http://hdl.handle.net/1721.1/64727 https://orcid.org/0000-0001-5486-2755 https://orcid.org/0000-0002-7112-1454 |
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