Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways

Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways

Two-component signal transduction systems enable bacteria to sense and respond to a wide range of environmental stimuli. Sensor histidine kinases transmit signals to their cognate response regulators via phosphorylation. The faithful transmission of information through two-component pathways and the...

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Bibliographic Details
Main Authors: Capra, Emily Jordan, Perchuk, Barrett, Lubin, Emma Alexandra, Ashenberg, Orr, Skerker, Jeffrey M., Laub, Michael T
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/64739
https://orcid.org/0000-0002-8288-7607

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http://hdl.handle.net/1721.1/64739
https://orcid.org/0000-0002-8288-7607

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