Current Challenges for Modeling Enzyme Active Sites by Biomimetic Synthetic Diiron Complexes

This tutorial review describes recent progress in modeling the active sites of carboxylate-rich non-heme diiron enzymes that activate dioxygen to carry out several key reactions in Nature. The chemistry of soluble methane monooxygenase, which catalyzes the selective oxidation of methane to methanol,...

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Bibliographic Details
Main Authors: Friedle, Simone, Reisner, Erwin, Lippard, Stephen J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Royal Society of Chemistry 2011
Online Access:http://hdl.handle.net/1721.1/64760
https://orcid.org/0000-0002-2693-4982