Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

Chemotherapy resistance is a major obstacle in cancer treatment, yet the mechanisms of response to specific therapies have been largely unexplored in vivo. Employing genetic, genomic, and imaging approaches, we examined the dynamics of response to a mainstay chemotherapeutic, cisplatin, in multiple...

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Bibliographic Details
Main Authors: Oliver, Trudy, Mercer, Kim L., Sayles, Leanne C., Burke, James R., Mendus, Diana, Lovejoy, Katherine S., Cheng, Mei-Hsin, Subramanian, Aravind, Mu, David, Powers, Scott, Crowley, Denise G., Bronson, Roderick T., Whittaker, Charles A., Bhutkar, Arjun (AJ), Lippard, Stephen J., Golub, Todd R., Thomale, Juergen, Jacks, Tyler E., Sweet-Cordero, E. Alejandro
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press in association with The Genetics Society 2011
Online Access:http://hdl.handle.net/1721.1/64761
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0002-2693-4982

Internet

http://hdl.handle.net/1721.1/64761
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0002-2693-4982

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