Phosphine-catalyzed asymmetric additions of malonate esters to gamma-substituted allenoates and allenamides

Because carbonyl groups are ubiquitous in organic chemistry, the ability to synthesize functionalized carbonyl compounds, particularly enantioselectively, is an important objective. We have developed a straightforward and versatile method for catalytic asymmetric carbon–carbon bond formation at the...

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Bibliographic Details
Main Authors: Sinisi, Riccardo, Sun, Jianwei, Fu, Gregory C.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/64786