Repair of DNA Alkylation Damage by the Escherichia coli Adaptive AlkB as Studied by ESI-TOF Mass Spectrometry

Repair of DNA Alkylation Damage by the Escherichia coli Adaptive AlkB as Studied by ESI-TOF Mass Spectrometry

DNA alkylation can cause mutations, epigenetic changes, and even cell death. All living organisms have evolved enzymatic and non-enzymatic strategies for repairing such alkylation damage. AlkB, one of the Escherichia coli adaptive response proteins, uses an α-ketoglutarate/Fe(II)-dependent mechani...

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Bibliographic Details
Main Authors: Li, Deyu, Delaney, James C., Page, Charlotte M., Chen, Alvin S., Wong, Cintyu, Essigmann, John M., Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: SAGE-Hindawi Access to Research 2011
Online Access:http://hdl.handle.net/1721.1/64788
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0001-6159-0778
https://orcid.org/0000-0002-2196-5691

Internet

http://hdl.handle.net/1721.1/64788
https://orcid.org/0000-0001-5486-2755
https://orcid.org/0000-0001-6159-0778
https://orcid.org/0000-0002-2196-5691

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