Repair of DNA Alkylation Damage by the Escherichia coli Adaptive AlkB as Studied by ESI-TOF Mass Spectrometry
DNA alkylation can cause mutations, epigenetic changes, and even cell death. All living organisms have evolved enzymatic and non-enzymatic strategies for repairing such alkylation damage. AlkB, one of the Escherichia coli adaptive response proteins, uses an α-ketoglutarate/Fe(II)-dependent mechani...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
SAGE-Hindawi Access to Research
2011
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| Online Access: | http://hdl.handle.net/1721.1/64788 https://orcid.org/0000-0001-5486-2755 https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0002-2196-5691 |