Thalamocortical model for a propofol-induced alpha rhythm associated with loss of consciousness

Recent data reveal that the general anesthetic propofol gives rise to a frontal α-rhythm [alpha rhythm] at dose levels sufficient to induce loss of consciousness. In this work, a computational model is developed that suggests the network mechanisms responsible for such a rhythm. It is shown that pro...

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Bibliographic Details
Main Authors: Ching, Shinung, Cimenser, Aylin, Purdon, Patrick Lee, Brown, Emery N., Kopell, Nancy J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences 2011
Online Access:http://hdl.handle.net/1721.1/64815
https://orcid.org/0000-0001-5651-5060
https://orcid.org/0000-0003-2668-7819