Thalamocortical model for a propofol-induced alpha rhythm associated with loss of consciousness
Recent data reveal that the general anesthetic propofol gives rise to a frontal α-rhythm [alpha rhythm] at dose levels sufficient to induce loss of consciousness. In this work, a computational model is developed that suggests the network mechanisms responsible for such a rhythm. It is shown that pro...
Main Authors: | Ching, Shinung, Cimenser, Aylin, Purdon, Patrick Lee, Brown, Emery N., Kopell, Nancy J. |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2011
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Online Access: | http://hdl.handle.net/1721.1/64815 https://orcid.org/0000-0001-5651-5060 https://orcid.org/0000-0003-2668-7819 |
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