Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

Much interest is currently focused on the emerging role of tumor-stroma interactions essential for supporting tumor progression. Carcinoma-associated fibroblasts (CAFs), frequently present in the stroma of human breast carcinomas, include a large number of myofibroblasts, a hallmark of activated fib...

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Bibliographic Details
Main Authors: Kojima, Yasushi, Acar, Ahmet, Eaton, Elinor Ng, Mellody, Kieran T., Scheel, Christina, Ben-Porath, Ittai, Onder, Tamer T., Wang, Zhigang C., Richardson, Andrea L., Weinberg, Robert A., Orimo, Akira
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/64942
https://orcid.org/0000-0002-0895-3557

Internet

http://hdl.handle.net/1721.1/64942
https://orcid.org/0000-0002-0895-3557

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