Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Much interest is currently focused on the emerging role of tumor-stroma interactions essential for supporting tumor progression. Carcinoma-associated fibroblasts (CAFs), frequently present in the stroma of human breast carcinomas, include a large number of myofibroblasts, a hallmark of activated fib...
Main Authors: | Kojima, Yasushi, Acar, Ahmet, Eaton, Elinor Ng, Mellody, Kieran T., Scheel, Christina, Ben-Porath, Ittai, Onder, Tamer T., Wang, Zhigang C., Richardson, Andrea L., Weinberg, Robert A., Orimo, Akira |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2011
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Online Access: | http://hdl.handle.net/1721.1/64942 https://orcid.org/0000-0002-0895-3557 |
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