A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
Decades of study have revealed more than 100 ribonucleoside structures incorporated as post-transcriptional modifications mainly in tRNA and rRNA, yet the larger functional dynamics of this conserved system are unclear. To this end, we developed a highly precise mass spectrometric method to quantify...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2011
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| Online Access: | http://hdl.handle.net/1721.1/64964 https://orcid.org/0000-0003-0011-3067 https://orcid.org/0000-0001-7940-3459 https://orcid.org/0000-0002-4607-5337 |