Mechanism of inactivation of influenza viruses by immobilized hydrophobic polycations

N,N-Dodecyl,methyl-polyethylenimine coatings applied to solid surfaces have been shown by us to disinfect aqueous solutions of influenza viruses. Herein we elucidate the mechanism of this phenomenon. Infectivity-, protein-, RNA-, and scanning electron microscopy-based experiments reveal that, upon c...

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Bibliographic Details
Main Authors: Hsu, Bryan Boen, Wong, Sze Yinn, Chen, Jianzhu, Klibanov, Alexander M., Hammond, Paula T
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/64967
https://orcid.org/0000-0003-3830-714X
https://orcid.org/0000-0002-5687-6154