MicroRNA miR-125b causes leukemia

MicroRNA miR-125b has been implicated in several kinds of leukemia. The chromosomal translocation t(2;11)(p21;q23) found in patients with myelodysplasia and acute myeloid leukemia leads to an overexpression of miR-125b of up to 90-fold normal. Moreover, miR-125b is also up-regulated in patients with...

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Bibliographic Details
Main Authors: Bousquet, Marina, Harris, Marian H., Zhou, Beiyan, Lodish, Harvey F
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2011
Online Access:http://hdl.handle.net/1721.1/64991
https://orcid.org/0000-0002-7029-7415