Most mammalian mRNAs are conserved targets of microRNAs

MicroRNAs (miRNAs) are small endogenous RNAs that pair to sites in mRNAs to direct post-transcriptional repression. Many sites that match the miRNA seed (nucleotides 2–7), particularly those in 3′ untranslated regions (3′UTRs), are preferentially conserved. Here, we overhauled our tool for finding p...

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Bibliografiske detaljer
Main Authors: Friedman, Robin Carl, Farh, Kyle Kai-How, Bartel, David, Burge, Christopher B
Andre forfattere: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Sprog:en_US
Udgivet: Cold Spring Harbor Laboratory Press in association with The Genetics Society 2011
Online adgang:http://hdl.handle.net/1721.1/65151
https://orcid.org/0000-0002-3872-2856