A Computational and Experimental Study of the Regulatory Mechanisms of the Complement System

The complement system is key to innate immunity and its activation is necessary for the clearance of bacteria and apoptotic cells. However, insufficient or excessive complement activation will lead to immune-related diseases. It is so far unknown how the complement activity is up- or down- regulated...

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Bibliographic Details
Main Authors: Liu, Bing, Zhang, Jing, Tan, Pei Yi, Hsu, David, Blom, Anna M., Leong, Benjamin, Sethi, Sunil, Ho, Bow, Ding, Jeak Ling, Thiagarajan, P. S.
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART)
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/65154