Cyclin-G-associated kinase modifies alpha-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study

Although family history is a well-established risk factor for Parkinson's disease (PD), fewer than 5% of PD cases can be attributed to known genetic mutations. The etiology for the remainder of PD cases is unclear; however, neuronal accumulation of the protein α-synuclein is common to nearly al...

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Bibliographic Details
Main Authors: Dumitriu, Alexandra, Pacheco, Chris D., Wilk, Jemma B., Strathearn, Katherine E., Latourelle, Jeanne C., Goldwurm, Stefano, Pezzoli, Gianni, Rochet, Jean-Christophe, Lindquist, Susan, Myers, Richard H.
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Format: Article
Language:en_US
Published: Oxford University Press 2011
Online Access:http://hdl.handle.net/1721.1/65570
https://orcid.org/0000-0003-1307-882X