A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

The 2009 H1N1 influenza A virus continues to circulate among the human population as the predominant H1N1 subtype. Epidemiological studies and airborne transmission studies using the ferret model have shown that the transmission efficiency of 2009 H1N1 viruses is lower than that of previous seasonal...

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Bibliographic Details
Main Authors: Jayaraman, Akila, Pappas, Claudia, Raman, Rahul, Belser, Jessica A., Viswanathan, Karthik, Tumpey, Terrence M., Sasisekharan, Ram, Shriver, Zachary H.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Public Library of Science 2011
Online Access:http://hdl.handle.net/1721.1/65575
https://orcid.org/0000-0002-1288-9965
https://orcid.org/0000-0001-9344-0205
https://orcid.org/0000-0002-2085-7840